Plumbagin from Ceratostigma willmottianum
نویسندگان
چکیده
منابع مشابه
Antimicrobial activity in vitro of plumbagin isolated from Plumbago species.
Plumbagin is a naturally occurring naphthoquinone isolated from roots of Plumbago scandens. The plant was collected at the Campus of Fundação Oswaldo Cruz, Rio de Janeiro, Brazil. P. scandens is used as a traditional medicine for the treatment of several diseases. The antimicrobial activity of plumbagin was evaluated using the macrodilution method. The compound exhibited relatively specific act...
متن کاملPlumbagin modulates leukemia cell redox status.
Plumbagin is a plant naphtoquinone exerting anti-cancer properties including apoptotic cell death induction and generation of reactive oxygen species (ROS). The aim of this study was to elucidate parameters explaining the differential leukemia cell sensitivity towards this compound. Among several leukemia cell lines, U937 monocytic leukemia cells appeared more sensitive to plumbagin treatment i...
متن کاملIn vitro callus induction and estimation of plumbagin content from Plumbago auriculata Lam.
The medicinal plant Plumbago contains a very potent secondary metabolite, plumbagin having many therapeutic properties. Callus culture was induced using explants, leaf, stem and shoot apex, from P. auriculata. Murashige and Skoog media fortified with various growth hormones like NAA, IAA, IBA and 2, 4-D individually and in various combinations were checked for callus induction. Among the growth...
متن کاملAntimalarial activity of plumbagin in vitro and in animal models
BACKGROUND Plumbagin is the major active constituent in several plants including Plumbago indica Linn. (root). This compound has been shown to exhibit a wide spectrum of biological and pharmacological activities. The present study aimed to evaluate the in vitro and in vivo antimalarial activity of plumbagin including its acute and subacute toxicity in mice. METHODS In vitro antimalarial activ...
متن کاملPlumbagin production by root cultures of Plumbago rosea
∗ Corresponding author Root cultures of Plumbago rosea Linn. were established from young leaf explants on solid Gamborg's B5 (B5) medium supplemented with the combination of αnaphthalene acetic acid (NAA) and kinetin in the concentration ranges of 0.5-2.0 mg/l and 0.1-0.5 mg/l, respectively. The production of plumbagin, determined by TLC-densitometry was higher [0.016 ± 0.0030% dry weight (DW)]...
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ژورنال
عنوان ژورنال: Chemistry of Natural Compounds
سال: 1974
ISSN: 0009-3130,1573-8388
DOI: 10.1007/bf00568230